By moving cell culture plates from the incubator to the workbench and back, the cells are exposed to variable levels of oxygen that quickly affect gene expression and cell morphology. Ideally, researchers keep their cultures at constant physiological oxygen concentrations even while conducting experiments. Closed bank culture systems mimic in vivo conditions by creating controlled environments in which parameters such as oxygen remain consistent. The researchers combine imaging and cell assays of living cells with these workstations to analyze their cultures under physiological conditions.
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