The genotyping of single nucleotide polymorphisms (SNPs) has revolutionized our understanding of human genetics. In addition, Next Generation Sequencing (NGS) enables researchers to sequence beyond SNPs to identify multiple allele sites, insertions, deletions, and other variants. NGS is flexible because researchers can design sequencing probes for specific regions of the genome. Targeted sequencing of SNPs and environment can be problematic on a large scale. However, new custom target enrichment panels capture and sequence regions of interest efficiently and reliably.
Download this application note from Twist Bioscience to learn more about the performance of custom target enrichment fields in capture-based SNP genotyping.